No one can live long without the will to go on, and mood swings can sometimes make us feel that life is too much for us. These episodes are often due to inner imbalances or deficiencies. The Europeans use supplements of a natural compound found in human cells to regulate mood and restore a healthy outlook. SAMe (S-adenosyl-L-methionine) is produced from methionine, an amino acid that plays a role in the production of “upside” neurotransmitters such as dopamine and serotonin. One study showed that SAMe worked on patients who had had no success with conventional antidepressants. Other clinical tests indicate the substance can also alleviate osteoarthritis and help repair the liver. To get a boost from SAMe, take a supplement combining it with vitamins B6, B12. It will remind you of what you already know: life is worth it!